|
The focus of Dr. Balasubramanian's research is to apply biofluid mechanical principles to the molecular and protein biology of hemostasis and thrombosis with the intention of making novel contributions, generating new paradigms and treatment strategies. She has recently been instrumental in describing a heretofore unknown circulating form of tissue factor present in normal human blood. One of her current research efforts is directed at studying this protein and characterizing its role in thrombosis in the human vasculature. The development of blood-compatible biomaterials that can be used as a substitute for diseased/damaged vascular tissue is another major area of Dr. Balasubramanian's research. Research conducted in her laboratory probes into the mechanisms by which flow, surfaces, and blood components interact in modulating vascular blockages that lead to heart attack and stroke.
Additionally, Dr. Balsubramanian has established numerous collaborations with The University of Chicago and Argonne National Laboratories fostering translational research. The overall goal of these joint projects (listed below) is to develop materials and techniques that can be used in specific patient populations for the treatment of various disorders such as neointimal hyperplasia, toxin removal from blood, and polymers for anti-cancer treatment. | 