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Dr. Ryser has served as one of our directors since September 1998. He serves on the Board's compensation committee. Since April 2000, Dr. Ryser has served as a managing director of Bear Stearns Health Innoventures, a venture capital fund. Dr. Ryser served as Chief Executive Officer until April 2000, and has served as a member and delegate of the board of International Biomedicine Management Partners Inc. From January 1989 until 1997, Dr. Ryser held various positions at Roche, including Scientific Assistant to the President of Global Research and Development, and was responsible for maintaining the scientific liaison between Roche and Genentech. Dr. Ryser received a Ph.D. degree in molecular biology from the University of Basel. | 