Dr. Rybak's practice is focused on the preparation and prosecution of patent and trademark applications.
Technical Expertise
Dr. Rybak's focus is biotechnology, including molecular biology, biochemistry, virology, and botany. She also prepares patentability opinions, prosecution and litigation of United States trademarks, and litigation legal research and support. In addition she prepares and prosecutes plant patents.
Bar Admissions
Oregon, 2003
U.S. Patent and Trademark Office (Reg. No. 47,913)
Prior Professional Experience
Oregon Health Sciences University, Portland, OR
Post-Doctoral Fellow, 1997 - 1998
Designed and constructed genetically engineered fluorescent-tagged proteins, examined trafficking of these proteins using real-time microscopy and developed in vitro protein binding assays;
National Institutes of Health post-doctoral Neuroendocrine Training Grant, 1997-1998
Carnegie Mellon University, Pittsburgh, PA
Department of Biological Sciences, Doctoral Candidate, 1992 - 1997
Developed cell biological and theoretical methods to study mechanisms of endosomal pH regulation
Phi Kappa Phi, National Honor Society (1996); American Society for Cell Biology predoctoral/student travel award to attend the 1995 meeting; American Heart Association, Pennsylvania Affiliate, student fellowship (1994-1996); National Science Foundation fellowship through Graduate Research Training Grant at the Center for Light Microscope Imaging and Biotechnology (1994-1996); National Institutes of Health award to attend the Physiology: Cellular and Molecular Biology course at the Marine Biological Laboratory, Woods Hole, Massachusetts (1994); Graduate Student Conference Presentation Grant from Carnegie Mellon University to attend the 1993 American Society for Cell Biology meeting.
University of Maryland at Baltimore, Baltimore, MD
Research Assistant, 1990 - 1992
Studied the effects of the calcium pool inhibitors on cell growth.
Presentations and Publications
Rybak, S. L. and R. F. Murphy. (2000). Measurement of ligand acidification kinetics for adherent and non-adherent cells. In Living Color: Flow Cytometry and Cell Sorting Protocols. R. Diamond and S. DeMaggio, editors. pp. 496-523.
Wan, L., S. S. Molloy, L. Thomas, G. Liu, Y. Xiang, S. L. Rybak, and G. Thomas. PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization. (1998). Cell 94:205-216.
Rybak, S. L., and R. F. Murphy. (1998). Primary cell cultures from murine kidney and heart differ in endosomal pH. J. Cell. Physiol. 176:216-222.
Rybak, S. L., F. Lanni and R. F. Murphy. (1997). Theoretical considerations on the role of membrane potential in the regulation of endosomal pH. Biophys. J. 73:674-687.
Benka, M. L., M. Lee, G.-R. Wang, S. Buckman, A. Burlacu, L. Cole, A. DePina, P. Dias, A. Granger, B. Grant, A. Hayward-Lester, S. Karki, S. Mann, O. Marcu, A. Nussenzweig, P. Piepenhagen, M. Raje, F. Roegiers, S. Rybak, A. Salic, E. Schultes, J. Smith-Hall, J. Waters, N. Yamamoto, J. Yanowitz, K. Yenw, W. Busa and M. E. Mendelsohn. (1995). The Thrombin Receptor in Human Platelets is Coupled to a GTP-binding protein of the Gq Family. FEBS Letters. 363:49-52.
Short, A. D., J. Bian, T. K. Ghosh, R. T. Waldron, S. L. Rybak, and D. L. Gill. (1993). Intracellular Ca2+ pool content is linked to control of cell growth. Proc. Natl. Acad. Sci. USA. 90:4986-4990.
Gill, D. L., T. K. Ghosh, J. Bian, A. D. Short , R. T. Waldron and S. L. Rybak. (1992). Function and Organization of the Inositol 1,4,5-Trisphosphate-Sensitive Calcium Pool. In Adv. Second Messenger Phosphoprotein Res. J.W. Putney, editor. 26:265-308.
Ghosh, T. K., J. Bian, A. D. Short, S. L. Rybak and D. L. Gill. (1991). Persistent Intracellular Calcium Pool Depletion by Thapsigargin and Its Influence on Cell growth. J. Biol. Chem. 266:24690-24697.
Honors and Awards
Best Appellate Brief for First Year Moot Court, Lewis and Clark Law School, 2000
Professional Activities
Member, Oregon State Bar Association, Multnomah Bar Association and American Bar Association
Oregon State Bar Legal Ethics Committee (2005-2007)
Representative Patents
Alanine 2,3-Aminomutase
Apple tree named `Irene`
CC chemokine receptor 5 DNA, new animal models and therapeutic agents for HIV infection
Floral homeotic genes for manipulation of flowering in poplar and other plant species
Heuchera plant named `Ginger Ale`
Hybrid seashore paspalum available from seed called `Sea Spray`
Lentivirus vector system
Oral treatment of hemophilia
Pear tree named `P448-2`
Poplar tree named ‘Gnarly Poplar’
Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer
Tall fescue variety having rhizomes
Transgenic plants expressing temporin peptides
Year Joined Firm
1998 |