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Mr. Zenner has been a director since May of 2002. Mr. Zenner is a 32-year veteran of the pharmaceutical industry and spent his entire career at Hoffmann-La Roche. During his first 12 years he held positions of increasing responsibility in sales marketing health care economics public policy and governmental affairs. In 1982 he became Vice-President and General Manager of Roche Laboratories and subsequently Director and Head of Global Pharma Marketing Project Development and Regulation in Basel Switzerland. In 1988 he became Senior Vice President Pharmaceuticals Division and a member of the Board of Directors. From 1993 until his retirement in 2001 he served as President and CEO of Hoffman-La Roche Inc. North America. Mr. Zenner currently serves on the Boards of Arqule Inc. Curagen Corporation Dendrite International Inc. Exact Sciences Corporation Geron Corporation Praecis Pharmaceuticals Inc. Sciele Pharma Inc. and West Pharmaceutical Services. He has also served as a member of the Board and the Executive Committee of both the Pharmaceutical Research and Manufacturers Association (PhRMA) and the Biotechnology Industry Organization (BIO). | 