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Joseph M. Mandato has served as one of our Directors since 2005. Mr. Mandato is a Managing Director of DeNovo Ventures, a venture capital firm, located in Menlo Park, CA. Earlier in his career, Mr. Mandato served as Chairman of Confer Software Inc., a developer of enterprise software used to automate healthcare business processes. Mr. Mandato also served as a vice president, member of the founding management committee and Chief Executive Officer of two of Guidant Corporation’s five operating units, Origin Medsystems and Heart Rhythm Technology, also serving as President and Chief Executive Officer of Origin Medsystems. Mr. Mandato also co-founded Gynecare, a developer of devices used in gynecology spun-out of Guidant Corporation and served as its Chief Executive Officer until April, 1995. From July, 1986 to November, 1990, Mr. Mandato was Chief Executive Officer of Ioptex Research, an ophthalmic device company. Mr. Mandato holds a B.S. from Nasson College, an M.A. from Long Island University, and a Doctor of Management degree from Case Western Reserve University. | 