Dr. Jonathan Jackson directs CellzDirect’s in vitro drug metabolism studies, including cytochrome P450 induction, inhibition and reaction phenotyping studies. Dr. Jackson received his doctorate in molecular and cellular toxicology from North Carolina State University in a graduate partnership program with the National Institute of Environmental Health Sciences (NIEHS). He was a pre-doctoral research fellow in the Human Metabolism Section in the NIEHS Laboratory of Pharmacology and Chemistry, under the direction of Drs. Joyce Goldstein and Masahiko Negishi. Dr. Jackson’s dissertation focused on the role of nuclear receptors in the drug-induced transcriptional activation of cytochrome P450 enzymes. As a postdoctoral research fellow, Dr. Jackson investigated the effects of nonalcoholic fatty liver disease on drug metabolism and disposition at the University of Arizona, under Dr. Nathan Cherrington. |