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Irwin Lerner has been a director since April 1999. Mr. Lerner served as chairman of the board and the executive committee of F. Hoffmann-La Roche Inc., a pharmaceutical and health care company, from January 1993 until his retirement in September 1993. From 1980 through December 1992, he also served as the president and chief executive officer of Roche. Since September 1995, Mr. Lerner has been on the board of Medarex Inc., a monoclonal antibodies products company; he became chairman of the board in May 1997. He served for 12 years on the board of the Pharmaceutical Manufacturers' Association, where he chaired the association's FDA Issues Committee. Mr. Lerner received a B.S. and an M.B.A. from Rutgers University. He is currently a Distinguished Executive-in-Residence at Rutgers University Graduate School of Management. Mr. Lerner is also a director of Humana Inc., a health care company; Covance Inc., a drug development services company; V.I. Technologies, Inc., a blood products company; Medarex, Inc.; and Reliant Pharmaceuticals LLC, a pharmaceutical company. | 