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Edward V. Fritzky has served as a director of the Company since July 1998. He served as a director and advisor to Amgen Corporation from July 2002 to May 2005. He served as Chief Executive Officer and Chairman of Immunex Corporation from January 1994 to July 2002. Mr. Fritzky is also a director of Sonosite Inc. and Jacobs Engineering Group Inc. Mr. Fritzky served as President of Lederle Laboratories a division of American Cyanamid from 1992 to 1994 and as Vice President of Lederle Laboratories from 1989 to 1992. Prior to joining Lederle Laboratories Mr. Fritzky was an executive of Searle Pharmaceuticals Inc. a subsidiary of the Monsanto Company. During his tenure at Searle Mr. Fritzky was Vice President of Marketing in the United States and later President and General Manager of Searle Canada Inc. and Lorex Pharmaceuticals a joint venture company. Mr. Fritzky is also the Trustee of the Fred Hutchinson Cancer Center. Mr. Fritzky holds a B.A. from Duquesne University and is a graduate of the Advanced Executive Program J.L. Kellogg Graduate School of Management at Northwestern University. | 