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Craig R. Smith M.D. joined the Company's board of directors in 2004 and currently serves as Chairman of the board of directors. Dr. Smith is currently the President of Williston Consulting LLC a firm providing advisory services to pharmaceutical and biotechnology companies. From 1993 to 2004 Dr. Smith served as the Chairman President and Chief Executive Officer of Guilford Pharmaceuticals Inc. a publicly held pharmaceutical company. He joined Guilford at its inception in 1993 and led its growth into a fully integrated pharmaceutical company with two marketed products and two products in Phase 3 clinical trials. From 1988 to 1992 Dr. Smith was Vice President of Clinical Research and from 1992 to 1993 Dr. Smith was Senior Vice President of Business and Market Development at Centocor Inc. a publicly held biotechnology company. From 1975 to 1988 he served on the faculty of the Department of Internal Medicine and Clinical Pharmacology at Johns Hopkins School of Medicine. He also serves on the boards of the Maryland Chapter of the Cystic Fibrosis Foundation the Greater Baltimore Committee and the Greater Baltimore High Tech Council. Dr. Smith is the Chair of the Advisory Council for the Institute of Basic Biomedical Sciences at Johns Hopkins University a member of the Johns Hopkins Alliance for Science and a member of the board of directors of Adams Express Company a publicly held closed-end equity investment company Depomed Inc. a publicly held specialty pharmaceutical company Petroleum & Resources Corporation a publicly held equity investment company specializing in energy and natural resources companies Oxxon Therapeutics a privately held company that focuses on immunotherapies to treat patients with chronic infectious diseases and cancer and Excigen Inc. a privately held company that focuses on gene therapy treatments. Dr. Smith holds an M.D. from the State University of New York at Buffalo and trained in Internal Medicine at Johns Hopkins Hospital from 1972 to 1975. | 