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The Vascular Engineering Laboratory researches the effects of fluid shear stress and mass transport on cellular haemostatic function and computational modeling of fluid flow and mass transport in coagulation reactions on the surface of biomaterials or vascular cells exposed to blood flow and the biocompatibility of nano-structured biomaterial polymer surfaces.
Specific projects include:
- Use of tissue factor pathway inhibitor to reduce thrombogencity of biomaterials surfaces
- Biocompatibility of nano-structure polymer coatings (in collaboration with Luping Yu and KaYee Lee, Chemistry, University of Chicago)
- Role of tissue factor expressed by endocardial endothelium in the thrombosis associated with non-ischemic dilated cardiomyopathy (NIDC) (in collaboration with Tony Kim, M.D., University of Chicago
- Modeling of Tissue Factor Pathway Inhibitor Coatings for Biomaterials: Effects of Flow and Substrate. | 