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Dr. Sherr was elected to the National Academy of Sciences in 1995 for outstanding contributions to retrovirology, oncogene characterization and function, receptor signaling, and cell cycle research.
Dr. Sherr studies oncogenes and tumor-suppressor proteins and is particularly interested in their role in governing mitogen-dependent progression through the mammalian cell division cycle. His laboratory focuses on how cells make a commitment to replicate their chromosomes and divide again or to withdraw instead into a quiescent state. In cancer cells, the molecular regulators that normally control this decision are so frequently disrupted by genetic damage that their loss may be essential for tumor formation.
Dr. Sherr, who joined the Stowers Institute Scientific Advisory Board in 2000, received an A.B. degree from Oberlin College and M.D. and Ph.D. degrees from New York University School of Medicine and Graduate School of Arts and Sciences. He was a member of the National Cancer Institute before joining St. Jude Children's Research Hospital in Memphis, Tennessee, where he is now a Howard Hughes Medical Institute investigator and the Herrick Foundation Chairman of the Department of Genetics and Tumor Cell Biology. | 