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Charles J. Homcy M.D. has served as a director of the Company since July 2005 and is currently president and chief executive officer of Portola Pharmaceuticals Inc. From January 2003 to November 2003 Dr. Homcy served as senior R&D advisor at Millenium Pharmaceuticals having joined them in 2002 as President Research and Development. Prior to that he served as executive vice president research and development of COR Therapeutics Inc. from 1995 to 2002 and as a director of COR from January 1998 to 2002. Since 1997 Dr. Homcy has been Clinical Professor of Medicine University of California at San Francisco Medical School and attending physician at the San Francisco VA Hospital. From 1994 until 1995 Dr. Homcy was president of the medical research division of American Cyanamid Company-Lederle Laboratories (now a division of Wyeth-Ayerst Laboratories). From 1990 until 1994 Dr. Homcy was executive director of the cardiovascular and central nervous system research section at Lederle Laboratories. From 1991 to 1995 Dr. Homcy also served as attending physician at The Presbyterian Hospital College of Physicians and Surgeons at Columbia University in New York. From 1979 to 1990 he was attending physician at Massachusetts General Hospital and an Associate Professor of Medicine at Harvard Medical School. Dr. Homcy is also a member of the board of directors of Millennium Pharmaceuticals Cytokinetics and Kosan Biosciences. Dr. Homcy received his B.A. and M.D. degrees from the Johns Hopkins University in Baltimore. | 